Infrastructure
The unique concept of EUNCL as a multi-competence service center offers a comprehensive and sophisticated portfolio of assay covering fields from chemical/physical to in vitro/in vivo characterization of promising nanomaterials. The tired characterization process is coordinated by a manager who also facilitates the communication with the sponsor.
CEA
| Test facility | Instrumental name | Producer | Model |
| physical chemical characterisation |
BET |
BEL Japan |
Belsorp Max |
| |
DLS (Dynamic Light scattering) PCS |
MALVERN |
ZetaSizer NanoZSP |
| |
AFM (Atomic Force Microscope) |
BRUKER |
Multimode |
| |
SEM (Scanning Electron Microscopy) |
ZEISS |
LEO 1530 |
| |
TEM (Transmission Electron Microscopy) |
TECNAI |
OSIRIS |
| |
FFF (Filed Flow fractionation) |
WYATT |
ECLIPSE |
| |
EDS (Electron Dispersive X-ray Spectrocopy) |
BRUKER |
Quantax xflash 5030 |
| |
ICP-MS (Ion Coupled Plasma Mass Spectroscopy) |
AGILENT |
7700X |
| |
UV-VIS AS (Ultra Violet and Visible light Absorption Spectroscopy) |
SHIMATSU |
|
| |
FTIR (Fourier Transform Infrared Spectroscopy) |
RIGAKU |
Nanohunter |
| |
NME ( Nuclear Magnetic Resonance) |
BRUKER |
AVANCE 200,400,500 |
| |
Pro-inflammatory cytokine detection (IL8 & TNF-alpha) |
BIORAD |
Bioplex MagPix |
| |
Endotoxin contamination using LAL test |
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Microbial contamination using PhEur-test |
About to be purchased |
|
| |
Mycoplasma contamination using PhEur test |
|
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More Informations (Website)
JRC
| Test facility | Instrumental name | Producer | Model |
| physical chemical characterisation |
Closed Vessel Microwave Digestion |
CEM Corporation |
Discover |
| |
Homogenizer |
GEA Mechanical Equipment SpA |
Panda |
| |
Disk Centrifuge Sedimentation |
CPS Instruments Inc. |
DC24000UHR |
| |
UV/Vis Spectrophotometer |
Thermo |
Nicolet Evolution 300 |
| |
Field-Flow Fractionation |
Postnova Analytics |
AF2000 AT |
| |
Field-Flow Fractionation |
Postnova Analytics |
PN4020 |
| |
Zeta Sizer |
Malvern Instruments Ltd |
NanoZS |
| |
Nanoparticle Analysis System |
Malvern Instruments Ltd |
Nanosight LM20 |
| |
Nanoparticle Sizer |
IZon |
Q-Nano |
| |
Circular Dichroism Spectrometer |
Jasco Corp. |
J-815 |
| |
Fluorescence Spectrometer |
Varian |
CARY Eclipse |
| |
Fourier Transform Infrared Spectrometer (FT-IR) |
Bruker |
Tensor27 |
| |
Fourier Transform Infrared Spectrometer (FT-IR) |
Bruker |
Vector22 |
| |
ICP-MS |
Agilent Technologies |
7700Series |
| |
Atomic Force Microscope 1 |
NT-MDT |
Solver |
| |
Atomic Force Microscope 2 |
Agilent Technologies |
AFM5500 |
| |
Surface Plasmon Resonance Imaging |
Horiba |
SPRi Plex |
| |
Fluorescence Lifetime Spectrometer |
ISS inc. |
Chronos FD |
| |
Ultramicrotome |
LEICA |
Cryo Leica EM VC7 |
| |
Automatic Plunge Freezing System |
LEICA |
EM GP |
| |
X-Ray Photoelectron Spectroscopy (XPS) |
Kratos Analytical Ltd. |
AXIS Ultra |
| |
ToF – SIMS |
ION-TOF GmbH |
TOF SIMS IV |
| |
Closed Vessel Microwave Digestion |
CEM Corporation |
Discover |
| |
Homogenizer |
GEA Mechanical Equipment SpA |
Panda |
| Imaging and Microcopy |
Transmission Electron Microscope |
JEOL Ltd. |
JEM2100 |
| |
Scanning Electron Microscopy – Focused Ion Beam |
FEI |
NOVA600 Dual Beam |
| |
Raman Confocal Microscope |
Witec |
Alpha300 |
| |
Fluoroscent mircoscope |
Zeiss |
Apotome+Axiovert 200 |
| |
Cell Imaging System |
GE Healthcare-Euroclone |
Incell2200 |
| Biology and Cell culture |
Multiwell plate reader |
Perkin Elmer |
Enspire |
| |
Flow Cytometer |
Partec |
CyFLOW space |
| |
Colony counter |
Oxford Optronix |
|
| |
Comet Microscope |
Andor comet |
|
| |
Electric cell impedance Sensing |
applied biophysics |
ECIS s Z |
| |
Lable free optical biosensor |
SDK biotechnologies |
Dynetix BR8 |
| |
Quartz Crystal Microbalance |
Biolin Scientific |
Q-Sense E4 |
| |
Imaging Nanoplasmonics |
Plasmore SRL |
Impressor 1.0 |
More Informations (Website)
SINTEF
| Test facility | Instrumental name | Producer | Model |
| in vitro toxicology |
Cell cultivation laboratory |
Several instruments. |
Several instruments |
| |
Liquid handling workstation |
Tecan |
Evo2 with MCA384 |
| |
Liquid handling workstation |
Beckman Coulter |
Orca system with NXP liquid handling robot |
| |
Flow cytometer |
Life technologies |
Attune |
| |
Automated microscope with onstage incubator |
Life technologies |
EwosFL Auto |
| |
Microplate reader |
Tecan |
Infinity 200Pro |
| |
Microplate reader |
Beckman Coulter |
Paradigm |
| |
UV/Vis Spectrophotometer, microplate reader |
Molecular Devices |
SpectraMAX384Plus |
| |
LC and LCMS system |
Agilent |
Agilent 1200 LC with 6490 QQQ MS |
| |
LC and LCMS system |
Agilent |
Agilent 1200 LC with 6510 QTOF MS |
| |
General cell cultivation laboratory |
Several instruments… |
Several instruments… |
More Informations (PDF, 0.5 MB)
TCD
| Test facility | Instrumental name | Producer | Model |
| In vivo toxicology |
Stabularium (Wistar rats (biodistribution), C57BL/6J strain mice (acute/chronic toxicity) |
ventilated cages (IVC system, Tecniplast, Italy) |
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| |
Histopathology laboratory |
standard equipment |
|
| |
Clinical chemistry |
standard equipment for assessing (ALT<AST<Serum Amyloid A, BUN, Bilirubin) |
|
More Informations (Website)
ULP
| Test facility | Instrumental name | Producer | Model |
| immunological characterisation |
MACSQuant flow cytometer |
Miltenyi Biotec |
MACSQuant |
| |
FACS Canto II Bioplex 200 |
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|
| |
Monochromatic plate reader with atmospheric control unit |
|
|
| |
automated cell separation equipment |
Miltenyi Biotec |
AutoMACS |
| hematological characterisation |
coagulometer |
Merlin MC4+ |
|
| physical characterisation |
dynamic light scattering (DLS) |
Malvern Instruments Ltd |
nanoZS |
| |
NMR spectroscopy |
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field flow fractionation |
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| |
isothermal titration calorimetry (ITC) |
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More Informations (PDF, 0.5 MB)
MUN
| Test facility | Instrumental name | Producer | Model |
| Analytical Chemistry (EU-NCL-relevant instruments) |
liquid chromatography (HPLC) |
Bruker |
EVOQ Advance UHPLC |
| |
capillary electrophoresis (CE) coupled with selective detectors including UV/vis absorbance, fluorescence and electrochemical |
Agilent |
CE and 3D CE |
| |
Gas chromatography (GC) equipped with Multi Purpose Sampler (MPS); GC coupled with selective detectors including mass spectrometric detector, FID |
Agilent |
G 1530 A |
| |
laser ablation (LA)-ICP-MS |
LA: CETAC coupled with ICP-MS: Thermo Fisher Scientific |
LSX-213 G2+ICAP Q ICP-MS |
| |
micro-X-Ray Fluorescence analysis (µXRF). |
Bruker |
M4 Tornado |
| |
ICP-MS |
Analytik Jena |
Plasmaquant-MS Elite |
| Tascon |
Time-of-Flight Secondary Ion Mass Spectrometry (ToF-SIMS) |
IONTOF |
TOF.SIMS5 |
| |
X-ray Photoelectron Spectroscopy (XPS) |
PHI |
Quantera |
| |
Low Energy Ion Scattering (LEIS) |
IONTOF |
q-tac 100 |
| |
White Light Interferometry/Confocal Height Measurements |
Sensofar |
Plu neox |
| BMTZ |
Cell cultivation laboratory |
Several instruments. |
Several Models |
| |
Cell culture incubator |
Heraeus/Thermo Scientific |
HeraCell several |
| |
Sterile work safety cabinets |
Heraeus/Thermo Scientific |
HeraSafe several |
| |
Cell counter and analyser |
Schärfe System GmbH |
CASY TT |
| |
Multi-point stirrer |
Thermo Scientific |
Variomag Telesystem 60 |
| |
Platewasher |
Dynex Technologies |
Opsys MW |
| |
Modular multimode reader with advanced liquid handling |
BMG Labtech |
NOVOstar |
| |
Fluorescence multi-mode microplate reader |
BMG Labtech |
FLUOstar Optima |
| |
LVF Monochromator multimode reader |
BMG Labtech |
CLARIOstar |
| |
Cryoscopic Osmometer |
Gonotec |
Osmomat 030 |
| |
DLS (Dynamic Light scattering) |
MALVERN Instruments |
ZetaSizer Nano-ZS |
| |
Ultrasonic device |
Hielscher, Brandson, Bandelin |
Diverse models |
| |
Concentrator |
Savant Instruments |
Speed Vac SC110 |
| |
Centrifuge |
Diverse models |
|
| |
Potentiometric STAT Titrator |
Methrom |
Titrando 902 |
| |
Microscopes, Fluorescence, Inverted, and diverse settings |
Olympus, Nikon |
IX-81; BX-41, IX-71, diverse |
| |
Digital holography microscopy |
diverse equipment |
|
| |
Microinjection |
Eppendorf |
FemtoJet+Injetman N12 |
| |
Microtome |
Microm |
Microm HM 315 |
| |
Fluorescence Imager / Chemo Luminescence Imager |
Intas Science Imaging |
Advanced Imager |
| |
Gel Imager |
Intas Science Imaging |
Gel iX Imager |
| |
General molecular biology laboratory |
Diverse equippment |
Diverse models |
| |
General protein biochemistry laboratory |
Diverse equippment |
Diverse models |
| |
Gel Electrophoresis and gel transfer |
BIORAD |
Multiple equipment |
| |
Sterilisation Autoclave |
Systec |
Vx-150 |
| |
In vitro cytotoxicity assays |
Matrix with different test methods available |
Up to 10 or more selected cell lines applicable for test matrix |
| |
Endotoxin contamination LAL test |
LAL based assays |
|
| |
Microbial contamination test |
Several test methods |
|
| |
Mycoplasma contamination test |
Nested PCR based assay |
|
| OxProtect |
Flow Cytometer |
Becton Dickinson |
Calibur |
| |
Platelet Aggregometer |
Mölab GmbH |
PAP-4 |
| |
Cell Counter |
Sysmex |
KX-21N |
| |
ELISA Reader |
Tecan |
Sunrise |
| |
Coagulometer |
Behnk |
Thrombotimer-4 |
| |
2D Electrophoresis |
Amersham |
Ettan IPGphor II |
| Vivo Science |
Elisa Reader |
Tecan |
Surise |
| |
Beta Counter |
Wallac |
Micro beta 1450 |
| |
FACS |
beckman coulter |
cytomics FC 500 |
| |
Mikrotomes |
Leica |
RM2245 |
| |
Tissue prossessing |
Medite |
TPC 15 DUO |
| |
Embedding station |
Bavimed |
FX 13 |
More Informations (Website)